The Difference Between Food Allergies and Food Intolerance

June 21, 2022

It is not uncommon for patients to report some unpleasant symptoms after eating certain foods. Most people blame these side effects on their food allergies or intolerances. Though these two terms are often used interchangeably and even share some of the same symptoms, they are not the same. Understanding the difference between the two is crucial to offering patients the critical care they need.


What Are Food Allergies?

The major difference between food allergies and food intolerance is that food allergies are an immune response. In contrast, food intolerance is caused by the inability of your digestive system to properly digest particular foods, usually because of an enzyme deficiency.

 

Unlike food intolerance, even small amounts of the allergen or food can trigger an allergy, which can often lead to life-threatening reactions, including anaphylactic shock. People don’t even need to eat a specific food to trigger an allergic reaction—just eating food that was prepared in an environment containing the allergen is enough to trigger a reaction.

 

In some cases, like Pollen Food Allergy Syndrome (PAFS), also known as oral allergy syndrome, the immune system recognizes pollen and similar proteins in some raw fruits, vegetables, and nuts and sets off an allergic reaction. Patients with PAFS can usually eat the same fruit or vegetable when it is cooked since the protein gets distorted when heated, making it unrecognizable to the immune system.


What Is Food Intolerance?

Food intolerance usually occurs when your digestive system struggles to break down a component in the food you eat. Lactose intolerance is the most common type of food intolerance, affecting around 10% of Americans. Though food intolerance can mimic the symptoms of allergies and can even be quite unpleasant, they are almost never fatal.


Symptoms

Food Intolerance

●    Sweating

●    Palpitations

●    Headache and Migraine

●    Diarrhea

●    Tightness across Face and Chest

●    Difficulty Breathing

●    Heartburn

●    Stomach Pain

●    Gas, Cramps, Bloating

●    Nausea and Vomiting


Food Allergies

Generally, symptoms caused by food allergies appear almost immediately after eating the food. As allergies are an immunological response, they react with several parts of the body.

 

●    Itching and Watering of the Eyes

●    Itching and Swelling of the Mouth

●    Swelling of the Throat and Airways

●    Stuffy and Runny Nose

●    It also Affects the Digestive System, Causing Stomach Pain, Vomiting, and Diarrhea

●    Skin Rashes, such as Hives or Atopic Dermatitis

●    Can Also Involve the Lungs, Resulting in Wheezing, Cough, and Asthma—Especially in Children

●    It also Interacts with the Central Nervous System, Causing Headaches, Irritability, Fatigue, and Convulsions


Diagnosis and Treatment

Food Intolerance

Most food intolerances are diagnosed through a trial and error method. You can ask the patient to keep a food diary to record what they eat and try to find patterns. A breath test can be used to diagnose lactose intolerance.

 

Avoiding the specific food for some time is the best solution. Individuals might even be able to reintroduce the food into their diet without any adverse effects after some time. But this might not always be the case as food intolerance cases can vary from patient to patient.


Food Allergies

Allergies can be diagnosed through the patch test, where the skin is exposed to the specific food. You can also use an oral challenge, where the patient ingests small controlled doses of food to monitor any adverse reactions.

 

Avoid foods that you're allergic to, and always keep an EpiPen handy in case of accidental exposure. Some allergy specialists also suggest treatments that can desensitize you to specific food allergies.

 

 

If you’re looking for more information on food allergies and food intolerance, get in touch with us at Snot Force Alliance Inc. We specialize in providing valuable information and opportunities to collaborate with ENT specialists across the country.


a-diverse-group-of-healthcare-professionals
February 17, 2026
Discover how to improve collaboration, communication, and trust between ENT specialists and allergists. Our guide provides actionable strategies for seamless patient care and stronger professional networks.
group of doctors working together
February 4, 2026
When standard sinusitis treatments fail, the cause is often dental. Discover why a strong partnership with an oral & maxillofacial specialist is non-negotiable for diagnosing and treating odontogenic sinusitis. Build your referral network today.
patient-being-checked-by-a-doctor-due-to-rhinosinusitis
January 22, 2026
Review the key symptoms, viral vs. bacterial differentiation, and evidence-based referral criteria for acute rhinosinusitis. Enhance diagnostic accuracy and patient management.
healthcare-and-medicine-ct-scan-of-human-sinuses
January 12, 2026
Explore how AI and deep learning are revolutionizing sinus & airway disease care—from high-accuracy CT analysis to automated pathology classification—while addressing key challenges in data privacy, workflow integration, and clinical adoption.
doctor-checking-the-throat-of-her-patient-in-a-clinic
December 1, 2025
A comprehensive guide to airway assessment from nose to lungs. Learn proactive evaluation techniques, physical exam steps, difficult airway prediction, and essential tools for nurses, RTs, paramedics, and physicians.
a young man sick with nasal congestion
November 25, 2025
Confidently distinguish chronic rhinitis from chronic sinusitis. Learn the key anatomic, diagnostic, and pathophysiologic differences, plus evidence-based treatment strategies every physician should know.
female-doctor-treating-the-asthma-of-a-pediatric-patient
October 8, 2025
Master the latest strategies for pediatric asthma. This 2025 specialist guide covers inhaler technique validation, environmental control, personalized monitoring, and advanced biologic therapies to improve outcomes and address disparities.
female-hiker-breathing-fresh-air-in-the-mountain
September 18, 2025
Chronic sinusitis is often a sign of a dysregulated immune system. This guide breaks down the sinus mucosa's immune role and the modern approach to treatment, including foundational care, surgery, and advanced biologics.
A young boy is blowing his nose into a napkin while sitting on a couch.
August 5, 2025
Recurrent pediatric sinusitis is often allergy-related. Learn how to identify, treat, and manage chronic sinus issues in kids—without overusing antibiotics.
A group of physicians working together.
July 22, 2025
Did you know 40% of maxillary sinusitis cases originate from dental issues? Learn how ENTs and dentists can collaborate to diagnose odontogenic sinusitis, when to refer patients, and key signs like unilateral pain or foul nasal taste.